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Why Lipids Matter Way More Than You Think (Especially If You’re a Woman)

June 28, 2025 by Functional Heart

Heart disease has a PR issue. For decades, it’s been portrayed as a man’s disease, balding heads, stress, steak dinners, and dramatic hospital scenes. But here’s the reality: heart disease is the number one killer of women, too.

And lipids? They’re often the silent saboteurs behind it all.

The Overlooked Danger

For years, women were left out of the heart conversation. Even their care lagged. Lipid issues in women were misread, dismissed, or simply ignored. The focus was often elsewhere: hormones, bones, breasts. But the heart?

It was treated like a side character.

Yet the truth is, women have just as much risk for atherosclerosis, the buildup of cholesterol-rich plaque inside artery walls, as men. In fact, they’re often diagnosed later, when the damage has already taken root.

Why? Because lipid disorders in women don’t always look the same. The symptoms are quieter. The clues, subtler. The traditional rules don’t always apply.

Lipids Tell a Story

Let’s decode this quickly.

Your bloodstream uses lipoproteins to move fats, cholesterol, and triglycerides through your body. The dangerous ones, the plaque-builders, are all wrapped in a protein called ApoB.

And here’s the key: Every ApoB particle can deposit cholesterol into your artery walls.

The more ApoB particles, the more potential damage, regardless of how “normal” your total cholesterol might look.

  1. LDL cholesterol might look fine.
  2. HDL might be high (the so-called “good cholesterol”).
  3. But ApoB? That’s the truth serum.

And most doctors don’t test for it, especially in women.

Hormones Add Another Twist

Women go through major hormonal shifts, puberty, pregnancy, and menopause. These can drastically affect lipid levels. Estrogen, for instance, offers some protective effects, but when it drops, especially after menopause, lipid risk can climb fast.

And here’s the kicker: many birth control pills and hormone replacement therapies can also affect lipids in unpredictable ways.

That’s why understanding a woman’s full health picture, not just her lipids, is essential.

So What Can You Do?

Don’t wait for symptoms. If you’re a woman, your heart deserves just as much attention as your hormones. Because lipids aren’t just numbers. They’re messengers. And they’ve been trying to warn us for years.

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